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Surface epithelial-stromal tumor
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Epithelial refers to the surface lining, and ovarian refers to ovary, of which women have two that sit along either side of the uterus so epithelial ovarian cancer, is a cancer that forms along the surface of an ovary.
Now, each ovary contains multiple follicles.
And, each follicle is made up of a germ cell, also known as an oocyte, which is the immature egg.
Now, if an epithelial cell starts to divide uncontrollably, it can either be a benign tumor which means that it does not invade nearby tissue or spread to other parts of the body, or it can be a malignant tumor which means that it might invade or spread to other tissues.
Compared with benign tumor cells, a distinguishing feature of malignant tumor cells have slightly less organized nuclei.
A third class of tumors are called borderline tumors because they have features that are intermediate between the other benign and malignant tumors.
Epithelial ovarian cancers can be subdivided into four types: serous, mucinous, endometrioid and transitional.
Serous and mucinous tumors arise from epithelial cells that line the outside of ovaries, whereas even though the tumors are found in the epithelium, the endometrioid and transitional cell tumors arise from other cell types.
Serous tumors have fluid-filled cysts, typically a single cyst, and can be benign, malignant, or borderline.
Benign serous tumors are called serous cystadenomas, and are the most common type, and often develop on both ovaries, and typically affect premenopausal women.
Mucinous tumors, on the other hand, have mucus-filled cysts that often involve large multiloculated cysts, but can also be benign, malignant, or borderline.
Surface epithelial-stromal tumors (SESTs), are tumors that arise from the ovarian surface epithelium, ectopic endometrial tissue, fallopian tube epithelium, or the endocervix. They can occur in many organs and tissues, including the ovaries, uterus, and other parts of the reproductive tract. These tumors can vary in size and type and can have variable clinical behaviors depending on the type. Treatment may include surgery, chemotherapy, radiation, and other therapies, depending on the type and severity of the tumor.
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