Syringomyelia
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Syringomyelia
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Syringomyelia
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Syringomyelia p. 506
Horner syndrome p. 559
spinal cord lesions p. 548
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Transcript
Contributors
Marisa Pedron
Tanner Marshall, MS
In syringomyelia, syrinx means cyst or cavity, and myelia means a condition of the spinal cord.
So, syringomyelia is a cystic enlargement of the spinal cord, and it typically starts medially and enlarges outwards, eventually damaging the spinothalamic tract, which is a part of the spinal cord that sends sensory signals about pain, pressure, temperature, and touch to the brain.
Now, the spinal cord itself is composed of both grey and white matter.
Grey matter is found within medial portion of the spinal cord and is shaped like a butterfly. This is where the cell bodies of different neurons can be found.
In the center of the grey matter there’s a small cavity the central canal which is filled with cerebrospinal fluid.
Cerebrospinal fluid helps provide nutrients and mechanical support to the brain and spinal cord.
Surrounding the grey matter is white matter, which consists of the axons of various neurons.
The spinal cord has different neural tracts that carry sensory information to and from the brain.
The corticospinal tract is a descending pathway which carries motor information from the brain to various muscles.
The dorsal column, located in the posterior portion of the spinal cord, is responsible for sensing pressure, vibration, fine touch, and proprioception, or the awareness of one’s body position in space.
Then there’s the spinothalamic tract, which is divided into two distinct tracts - the lateral spinothalamic tract which is responsible for sensing pain, pressure, and temperature, as well as the anterior spinothalamic tract which senses crude touch.
Summary
Syringomyelia refers to a condition in which a fluid-filled cavity, or syrinx, develops within the spinal cord, and it is most commonly caused by an Arnold-Chiari II malformation. The expanding cavity interferes with the spinothalamic tract which is responsible for pain, pressure, temperature, and crude touch, and results in the loss of these sensations in a cape-like distribution along the arms and back.
Syringomyelia may cause pain, paralysis, weakness, Horner syndrome, and stiffness in the back, shoulders, and extremities. In some cases, it can cause scoliosis or an abnormal curvature of the spine. Treatment depends on the severity of the condition and may include medications, physical therapy, and surgery.
Sources
- "Robbins Basic Pathology" Elsevier (2017)
- "Harrison's Principles of Internal Medicine" McGraw Hill Education/ Medical (2018)
- "Pathophysiology of Disease: An Introduction to Clinical Medicine 8E" McGraw-Hill Education / Medical (2018)
- "CURRENT Medical Diagnosis and Treatment 2020" McGraw-Hill Education / Medical (2019)
- "Post-traumatic syringomyelia (cystic myelopathy): a prospective study of 449 patients with spinal cord injury." Journal of Neurology, Neurosurgery & Psychiatry (1996)
- "Scoliosis associated with syringomyelia: analysis of MRI and curve progression" European Spine Journal (2007)
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