TF/Px ratio and TF/Pinulin
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High Yield Notes
10 pages
Questions
USMLE® Step 1 style questions USMLE
0 of 1 complete
A group of researchers is examining the relative concentrations of several substances along the proximal convoluted tubule. They discover one substance that is ideal for estimating the glomerular filtration rate. This substance is denoted by which of the following lines detailed in the graph below?
Summary
The [TF/P]x ratio refers to the ratio between the concentration of a substance "x" in the tubular fluid (TF) and the plasma (P) in a nephron. This ratio provides information about the reabsorption or secretion of a substance in the nephron.
The [TF/P]inulin ratio is a measurement of glomerular filtration rate (GFR), which is a measure of how well the kidneys are functioning. Inulin is a polysaccharide that is freely filtered by the glomerulus and is neither reabsorbed nor secreted by the tubules.
Both [TF/P]x ratio and [TF/P]inulin measurements can provide valuable information on renal function.