Thrombotic thrombocytopenic purpura (NORD)

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Pathology

Hematological system

Anemias
Heme synthesis disorders
Coagulation disorders
Platelet disorders
Mixed platelet and coagulation disorders
Thrombosis syndromes (hypercoagulability)
Lymphomas
Leukemias
Leukemoid reaction
Dysplastic and proliferative disorders
Plasma cell dyscrasias
Hematological system pathology review

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Thrombotic thrombocytopenic purpura (NORD)

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High Yield Notes
6 pages
Flashcards

Thrombotic thrombocytopenic purpura (NORD)

8 flashcards
Preview

Glucocorticoids are indicated for (hereditary/acquired) thrombotic thrombocytopenic purpura.

Questions

USMLE® Step 1 style questions USMLE

3 questions

USMLE® Step 2 style questions USMLE

2 questions
Preview

A 16-year-old Caucasian girl is brought to the emergency department by her mother because of a 5-day history of fever, fatigue, and "strange behavior". Her medical history is noncontributory.  Upon further interrogation, the girl reports that she "hears voices" telling her that "she has been chosen to be the new savior of god". On physical exam, the patient is disoriented. Further inspection shows skin jaundice, conjunctival pallor, and petechial rashes over her face and shoulders. Her temperature is 38.6°C (101.48°F), pulse is 131/min, respirations are 18/min, blood pressure is 130/70 mmHg. Laboratory studies show a decreased platelet count, increased creatinine and blood urea nitrogen, and increased indirect bilirubin. A peripheral blood smear is obtained and shown below.



               

Which of the following is the most likely cause of this patient's condition? 

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