Type I hypersensitivity
Autoimmune hemolytic anemia
Hemolytic disease of the newborn
Rheumatic heart disease
Type II hypersensitivity
Systemic lupus erythematosus
Type III hypersensitivity
Type IV hypersensitivity
Common variable immunodeficiency
Hyperimmunoglobulin E syndrome
IgG subclass deficiency
Isolated primary immunoglobulin M deficiency
Selective immunoglobulin A deficiency
Adenosine deaminase deficiency
Hyper IgM syndrome
Severe combined immunodeficiency
Cytomegalovirus infection after transplant (NORD)
Post-transplant lymphoproliferative disorders (NORD)
Chronic granulomatous disease
Leukocyte adhesion deficiency
Blood transfusion reactions and transplant rejection: Pathology review
Immunodeficiencies: Combined T-cell and B-cell disorders: Pathology review
Immunodeficiencies: Phagocyte and complement dysfunction: Pathology review
Immunodeficiencies: T-cell and B-cell disorders: Pathology review
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thymoma association p. 96
myasthenia gravis and p. 219, 479
paraneoplastic syndromes p. 219
Thymoma is a rare type of tumor that arises from the epithelial cells of the thymus gland that is located in the chest behind the breastbone. Thymomas may not cause any symptoms in the early stages of the disease, but as they grow and compress the nearby structures, causing symptoms like superior vena cava syndrome, dysphagia, cough, or chest pain.
Thymomas are frequently associated with the neuromuscular disorder myasthenia gravis or autoimmune conditions like pure red cell aplasia and Good syndrome. Diagnosis of thymoma involves imaging studies such as CT or MRI scans. A biopsy may also be performed to confirm the diagnosis. Treatment options may include surgery to remove the tumor, radiation therapy, chemotherapy, or a combination of these approaches.
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