Toxoplasma gondii (Toxoplasmosis)

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Toxoplasma gondii (Toxoplasmosis)

Parasitology

Protozoa

Plasmodium species (Malaria)

Babesia

Giardia lamblia

Entamoeba histolytica (Amebiasis)

Cryptosporidium

Acanthamoeba

Naegleria fowleri (Primary amebic meningoencephalitis)

Toxoplasma gondii (Toxoplasmosis)

Trypanosoma brucei

Trypanosoma cruzi (Chagas disease)

Trichomonas vaginalis

Leishmania

Worms

Loa loa (Eye worm)

Toxocara canis (Visceral larva migrans)

Onchocerca volvulus (River blindness)

Ascaris lumbricoides

Anisakis

Angiostrongylus (Eosinophilic meningitis)

Ancylostoma duodenale and Necator americanus

Strongyloides stercoralis

Guinea worm (Dracunculiasis)

Wuchereria bancrofti (Lymphatic filariasis)

Trichinella spiralis

Enterobius vermicularis (Pinworm)

Trichuris trichiura (Whipworm)

Echinococcus granulosus (Hydatid disease)

Diphyllobothrium latum

Paragonimus westermani

Clonorchis sinensis

Schistosomes

Ectoparasites

Pediculus humanus and Phthirus pubis (Lice)

Sarcoptes scabiei (Scabies)

Assessments

Toxoplasma gondii (Toxoplasmosis)

Flashcards

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USMLE® Step 1 questions

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High Yield Notes

6 pages

Flashcards

Toxoplasma gondii (Toxoplasmosis)

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Questions

USMLE® Step 1 style questions USMLE

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A 1-day-old girl is admitted to the neonatal intensive care unit for evaluation of jaundice and microcephaly. The infant was delivered by cesarean section at 36 weeks due to fetal growth restriction. Hepatosplenomegaly, intracranial calcifications and microcephaly were detected by ultrasonography during the patients gestation. The mother remained in the northeast United States for the duration of her pregnancy and did not travel. Vital signs are within normal limits. Physical examination demonstrates jaundice and widespread petechiae. The liver is palpable 5 cm below the costal margin. MRI brain reveals hydrocephalus and diffuse intracranial calcifications. Fundoscopy is notable for the finding as demonstrated below. Which of the following maternal exposures is the most likely etiology of this patient’s clinical condition?  


Reproduced from: wikipedia 

External References

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Blueberry muffin rash

Toxoplasma gondii p. , 181

Brain abscesses

Toxoplasma gondii p. , 174

Cats, (disease vectors)

Toxoplasma gondii p. , 153, 181

Hydrocephalus p. 540

Toxoplasma gondii p. , 181

Lymphadenopathy

Toxoplasma gondii p. , 181

Pyrimethamine p. 34, 197

Toxoplasma gondii p. , 723

Sulfadiazine p. 191

Toxoplasma gondii p. , 153, 723

Toxoplasma spp. p. 177

Toxoplasma gondii p. , 153

HIV-positive adults p. 174

labs/findings p. 720

ToRCHeS infection p. 181

treatment p. 723

External Links

Summary

Toxoplasma gondii is an obligate intracellular, parasitic protozoan that causes the disease toxoplasmosis. It is found worldwide and is capable of infecting virtually all warm-blooded animals, but felids such as domestic cats are the only known definitive hosts in which the parasite can undergo sexual reproduction. Cleaning cat litter boxes is a potential route of infection.

Transmission is by ingesting cysts in undercooked meat. If transmission occurs in a pregnant woman, the fetus can acquire congenital toxoplasmosis, whose features consist of the triad of chorioretinitis, hydrocephalus, and intracranial calcifications. Most healthy people recover from toxoplasmosis without treatment. However, ill individuals can be treated with druglike pyrimethamine, sulfadiazine, and folinic acid.

Elsevier

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