Tubular reabsorption and secretion of weak acids and bases

Summary of Tubular reabsorption and secretion of weak acids and bases
Many substances secreted by the proximal tubule are weak acids or weak bases. These can exist in either the uncharged or charged forms and the relative amount of each form depends on the pH of the tubular fluid. Uncharged weak acids and bases are able to diffuse back into the blood more freely than the charged form. 

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Tubular reabsorption and secretion of weak acids and bases

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Tubular reabsorption and secretion of weak acids and bases

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At an acidic pH, the (uncharged/charged) base-form of a weak base is the dominant form.