Video - Water-soluble vitamin deficiency and toxicity: B1-B7: Pathology review

Water-soluble vitamin deficiencies are mainly caused by insufficient dietary intake and chronic alcohol abuse. Their toxicities or hypervitaminosis can be caused by excess intake of supplements, fortified foods, or vitamin derivative-containing medications, but this is rare. Various types of vitamin B deficiencies can result in distinct health issues. Vitamin B1, or thiamine deficiency can cause Wernicke encephalopathy and beriberi. Vitamin B2, or riboflavin, deficiency can lead to angular cheilosis, glossitis, and corneal neovascularization.

Vitamin B3, or niacin, deficiency can cause pellagra, which presents with diarrhea, dementia, and dermatitis. Vitamin B5, or pantothenic acid deficiency can cause enteritis, adrenal insufficiency, dermatitis, alopecia, and burning feet syndrome. � Vitamin B6, or pyridoxine deficiency can lead to peripheral neuropathy and sideroblastic anemia. Vitamin B7, or biotin, deficiency can cause alopecia, dermatitis, and enteritis.