Acute leukemia Quiz: Ace Your Exams

Get ready to dominate your medical and nursing exams by using our dynamic quizzes to elevate your knowledge and increase your confidence. Whether you're gearing up for the USMLE®, COMLEX®, or your next in-class assessment, Osmosis quizzes tackle key topics in pathology, diagnostics, and treatment approaches. By honing in on clinical readiness and decision-making, we make sure the knowledge you gain empowers you both in the classroom and in real-world practice. Jump in and supercharge your exam prep!

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A 60-year-old man presents to the clinic because of progressive fatigue, fevers, and night sweats for the past 3 months. Past medical history is significant for 3 episodes of sinusitis in the last 6 months, which all resolved with the use of oral antibiotics. Temperature is 38.3°C (101°F), pulse is 105/min, respirations are 20/min, and blood pressure is 135/85 mmHg. Physical examination shows mucosal pallor and purpuric rashes on lower extremities. There is no lymphadenopathy.  
 
 Laboratory value  Result 
Complete blood count 
Hemoglobin   8.5 g/dL 
 Platelet count   70,000/mm3 
 Leukocyte count   6,000/mm3 
After appropriate workup, bone marrow biopsy reveals the following:  

A microscopy image shows a cluster of large, irregular cells with prominent nuclei, some surrounding smaller, red cells. Cells are varied in size and shape.
Reproduced from: Wikimedia Commons  
Which of the following is the most likely diagnosis in this patient? 

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