Ankylosing spondylitis Quiz: Ace Your Exams

Get ready to dominate your medical and nursing exams by using our dynamic quizzes to elevate your knowledge and increase your confidence. Whether you're gearing up for the USMLE®, COMLEX®, or your next in-class assessment, Osmosis quizzes tackle key topics in pathology, diagnostics, and treatment approaches. By honing in on clinical readiness and decision-making, we make sure the knowledge you gain empowers you both in the classroom and in real-world practice. Jump in and supercharge your exam prep!

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A 35-year-old man presents for follow-up after being treated for low back pain that improves with exercise and worsens with rest. He was prescribed medical treatment for this condition 6 weeks ago, and he has been taking the medications as prescribed but continues to have pain and stiffness. On physical examination, there is decreased lumbar flexion and pain in the sacroiliac joints with direct palpation. Laboratory findings include elevated C-reactive protein and ESR levels, and a negative HLA-B27. Radiographs of the sacroiliac joints show evidence of bilateral sacroiliitis. The patient is started on etanercept therapy. Which of the following would be an indication for initiating a TNF inhibitor in this patient?  

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