Approach to household substance exposure (pediatrics) Quiz: Ace Your Exams

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A 3-year-old boy is brought to the emergency department for evaluation after being found with an open, unmarked bottle of liquid in the living room. The child is otherwise healthy and does not take any medications daily. Temperature is 37°C (98.6°F), heart rate is 108/min, blood pressure is 105/67 mmHg, respiratory rate is 27/min, and oxygen saturation is 99% on room air. On physical examination, the child appears fatigued. Cardiopulmonary and abdominal examinations are within normal limits. A venous blood gas reveals a pH of 7.42. Additional laboratory findings are obtained and detailed below. Which of the following is the most likely diagnosis?

 Laboratory value Result
 Serum chemistry
 Sodium 142 mEq/L
 Potassium 4.2 mEq/L
 Chloride  107 mEq/L
 Bicarbonate 28 mEq/L
 Blood urea nitrogen (BUN) 18
 Creatinine 0.5 mg/dL
  Glucose 90
 Albumin 3.2 g/dL
 Serum osmolality 328 mOsm/kg

 Urinalysis
 Color Clear
 Specific gravity 1.013
 Glucose Negative
 Blood Negative
 Leukocyte esterase Negative
 Nitrites Negative
 Leukocytes 1-2/hpf
 Erythrocytes 1-2/hpf
 Dysmorphic RBCs Absent
 Ketones Large

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