Approach to myeloproliferative neoplasms Quiz: Ace Your Exams
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A 45-year-old man presents to his primary care physician with a 3-month history of fatigue, 10-lb weight loss, and night sweats. He reports a feeling of fullness in his left abdomen, which he notes has become more prominent. Temperature is 37°C (98.6°F), heart rate is 90/min, respiratory rate is 16/min, blood pressure is 124/77 mm Hg, and oxygen saturation is 98% on room air. The spleen tip is palpable on abdominal examination. Laboratory results are shown below. Which of the following additional tests should be performed next to confirm the diagnosis?
| Test | Result |
| Leukocytes | 39,180 mm3 |
| Hemoglobin | 13.0 g/dL |
| Hematocrit | 40.% |
| Platelets | 216,000 /mm³ |
| Differential | |
| Neutrophils | 67% |
| Bands | 9% |
| Lymphocytes | 7% |
| Monocytes | 2% |
| Eosinophils | 3% |
| Basophils | 4% |
| Metamyelocytes | 3% |
| Myelocytes | 5% |
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