Approach to peripheral lymphadenopathy Quiz: Ace Your Exams

Get ready to dominate your medical and nursing exams by using our dynamic quizzes to elevate your knowledge and increase your confidence. Whether you're gearing up for the USMLE®, COMLEX®, or your next in-class assessment, Osmosis quizzes tackle key topics in pathology, diagnostics, and treatment approaches. By honing in on clinical readiness and decision-making, we make sure the knowledge you gain empowers you both in the classroom and in real-world practice. Jump in and supercharge your exam prep!

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A 67-year-old man presents to the emergency department with a 2-week history of progressive shortness of breath, facial swelling, and a feeling of fullness in his head, especially upon waking. His past medical history is significant for stage IV non-Hodgkin lymphoma diagnosed 8 months ago. Temperature is 37.5 °C (99.5 °F), blood pressure is 105/70 mmHg, heart rate 114 beats/min, respiratory rate 22 breaths/min, and oxygen saturation 88% on room air. On physical examination, he appears distressed, with evident facial and upper extremity edema, and distended neck veins. There is no respiratory stridor, and the lung fields are clear on auscultation. Nontender cervical and axillary lymphadenopathy is present. A portable chest x-ray demonstrates significantly enlarged mediastinal lymph nodes. What is the best next step in management?  

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