Approach to prenatal teratogen exposure Quiz: Ace Your Exams
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A newborn boy delivered via cesarean section at 39 weeks’ gestation is evaluated for abnormal craniofacial features and bruising. Maternal history is notable for mechanical mitral valve replacement following rheumatic heart disease. No prenatal care was received during this pregnancy. The newborn was delivered with Apgar scores of 7 and 9 at 1 and 5 minutes, respectively, with no need for resuscitation. Birth weight was at the 50th percentile, length at the 10th percentile, and head circumference at the 35th percentile. Temperature is 37°C (98.6°F), pulse is 175/min, respirations are 40/min, blood pressure is 76/45 mmHg, and oxygen saturation is 97% on room air. On physical examination, a flat nasal bridge, small nose, and multiple bruises on the upper extremities are noted. Cardiopulmonary and abdominal examinations are unremarkable. Which of the following is the most likely cause of this patient’s symptoms?
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