Approach to vasculitis Quiz: Ace Your Exams
Get ready to dominate your medical and nursing exams by using our dynamic quizzes to elevate your knowledge and increase your confidence. Whether you're gearing up for the USMLE®, COMLEX®, or your next in-class assessment, Osmosis quizzes tackle key topics in pathology, diagnostics, and treatment approaches. By honing in on clinical readiness and decision-making, we make sure the knowledge you gain empowers you both in the classroom and in real-world practice. Jump in and supercharge your exam prep!
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A 42-year-old man presents to the clinic with a 3-month history of pain and ulcerations on his fingertips. He has a past medical history of asthma, seasonal allergies, and tobacco use disorder. He has smoked 1 pack per day for the past 30 years. He does not use alcohol or other recreational substances. He has no respiratory symptoms, hemoptysis, joint pains, oral or genital ulcers, or recent visual changes. Vitals are within normal limits. Examination reveals digital ulcers and gangrene on several fingertips. Pulses in his lower extremities are diminished, and there are multiple tender superficial nodules along the veins in his arms and legs bilaterally. Laboratory results are shown below. Angiography of the upper and lower extremities shows segmental arterial occlusions with corkscrew collaterals. Which of the following is the most likely diagnosis?
| Laboratory study | Result |
| Creatinine | 0.8 mg/dL |
| Antinuclear antibodies (ANA) | Negative |
| Anti-myeloperoxidase (anti-MPO) antibodies | Negative |
| Antiproteinase-3 antibodies | Negative |
| Anti-glomerular basement membrane (anti-GBM) antibodies | Negative |
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