Biliary atresia Quiz: Ace Your Exams
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A 4-week-old female is brought to the pediatric PA for evaluation of jaundice which began 3 weeks ago. In addition, according to the mother, the patient’s urine has become progressively darker and is “yellowish-brown” in color. The patient was born at 40 weeks gestation via an uncomplicated vaginal delivery. Her blood is type A, Rh-negative. The mother’s blood is type AB, Rh-positive. The patient is exclusively breastfed and products between 6-7 wet diapers daily. Physical examination shows scleral icterus, as well as jaundice of the head and neck. Abdominal exam is notable for a firm and enlarged liver. The remainder of the physical examination is noncontributory. Laboratory testing reveals the following findings:
Which of the following best describes the most likely cause of this patient’s finding?
| Laboratory value | Result |
| Total bilirubin | 7.2 mg/dL (reference range: 0.1-1 mg/dL) |
| Conjugated bilirubin | 6.5 mg/dL (reference range: 0.0-0.3 mg/dL) |
| Alkaline phosphatase | 115 U/L (20-70 U/L) |
Which of the following best describes the most likely cause of this patient’s finding?
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