Calcium pyrophosphate deposition disease (pseudogout) Quiz: Ace Your Exams
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A 68-year-old woman presents to the clinic with bilateral knee, wrist, and hand pain and swelling over the past year. She experiences morning stiffness lasting over 30 minutes. Past medical history is significant for subclinical hyperthyroidism, hypertension, and type 2 diabetes. She takes lisinopril and metformin. BMI is 32 kg/m². Temperature is 36.8°C (98.2°F), heart rate is 78/min, blood pressure is 145/90 mm Hg, and respiratory rate is 16/min. Physical examination reveals bilateral knee effusions, with tenderness and limited range of motion. Both wrists and multiple metacarpophalangeal joints on both hands are enlarged and tender to palpation. Laboratory evaluation is unremarkable. X-ray of the right knee is shown below, displaying chondrocalcinosis. Which of the following factors most likely contributed to the development of this patient’s underlying condition?

Taken from openi

Taken from openi
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