Cirrhosis Quiz: Ace Your Exams

Get ready to dominate your medical and nursing exams by using our dynamic quizzes to elevate your knowledge and increase your confidence. Whether you're gearing up for the USMLE®, COMLEX®, or your next in-class assessment, Osmosis quizzes tackle key topics in pathology, diagnostics, and treatment approaches. By honing in on clinical readiness and decision-making, we make sure the knowledge you gain empowers you both in the classroom and in real-world practice. Jump in and supercharge your exam prep!

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A 49-year-old woman comes to her primary care PA for evaluation of abdominal pain and itching. The symptoms began several months ago but have progressively worsened. Past medical history is significant for celiac disease, which is well managed with a gluten-free diet. She does not smoke, drink alcohol, or use illicit drugs. Vitals are within normal limits. BMI is 21 kg/m2. Physical examination reveals mild hepatomegaly. There is no scleral icterus or jaundice. Laboratory results are as follows:  

Laboratory Value  
Result
Leukocytes
8,000/mm3 (reference range: 4.500-11,000/mm3)  
Creatinine
0.7 mg/dL (reference range: 0.6-1.2 mg/dL)  
Total bilirubin  
4.1 mg/dL (reference range: 0.1-1 mg/dL)  
Conjugated bilirubin
1.3 mg/dL (reference range: 0.0-0.3 mg/dL)  
Alkaline phosphatase  
57 U/L (reference range: 20-70 U/L)  
Glucose
92 mg/dL (reference range: 70-110 mg/dL)  
AST
140 U/L (reference range: 8-40 U/L)  
ALT
154 U/L (reference range: 8-40 U/L)  
Anti-smooth muscle antibodies  
Positive (reference range: negative)  

A liver biopsy is performed. Which of the following histopathological changes would most likely be seen in this patient?  

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