Cystic fibrosis Quiz: Ace Your Exams

Get ready to dominate your medical and nursing exams by using our dynamic quizzes to elevate your knowledge and increase your confidence. Whether you're gearing up for the USMLE®, COMLEX®, or your next in-class assessment, Osmosis quizzes tackle key topics in pathology, diagnostics, and treatment approaches. By honing in on clinical readiness and decision-making, we make sure the knowledge you gain empowers you both in the classroom and in real-world practice. Jump in and supercharge your exam prep!

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A 3-year-old boy is brought to the clinic by his parent due to 3 days of productive cough and fever. The child was adopted at the age of 1, and the history of the patient’s biological family is unknown. The patient is at the 35th percentile for length and below the 10th for weight. The patient’s temperature is 39.0°C (102.2°F), pulse is 114/min, respirations are 22/min, and blood pressure is 104/75 mmHg. Examination reveals tachypnea and use of accessory muscles. There are decreased breath sounds heard over the left lower lung. Chest x-ray reveals lower left lobar consolidation. The parent states that the patient has had 3 similar episodes in the past year. Further genetic testing reveals a homozygous ΔF508 deletion. Which of the following is the most likely underlying cause for this patient’s condition?

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Degradation of mRNA encoding an ion channel

Hypermethylated gene encoding a transmembrane protein

Impaired glycosylation of extracellular protein

Abnormally early stop codon that halts protein production

Ubiquitinated abnormal transmembrane protein