Cystic fibrosis Quiz: Ace Your Exams
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A 14-year-old boy is brought to the physician for a routine checkup by his parents. The patient has a past medical history of recurrent pneumonia requiring multiple hospitalizations for intravenous antibiotic therapy. The patient was adopted at a young age and his parents lack information on his biological family history. They state that the patient has had episodes of chronic, foul-smelling diarrhea for the past several years. Vitals are within normal limits. Lung auscultation reveals occasional crackles. The liver is palpated 3 cm below the costal margin and is not tender. Laboratory results are as follows:
Which of the following is the most likely cause for this patient’s abnormal laboratory results?
| Laboratory value | Result |
| Aspartate aminotransferase | 67 U/L |
| Alanine aminotransferase | 72 U/L |
| Alkaline phosphatase | 142 U/L |
| Total bilirubin | 1.0 mg/dL |
| Direct bilirubin | 0.3 mg/dL |
| p-ANCA | Negative |
Which of the following is the most likely cause for this patient’s abnormal laboratory results?
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