Disorders of sex chromosomes Quiz: Ace Your Exams

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A 16-year-old girl presents to the family physician with concerns of delayed pubertal development. The patient has not yet had menarche and is concerned she is “falling behind” her classmates. According to her parent, the patient has been previously diagnosed with a chromosomal abnormality. Temperature is 37.7°C (99.9°F), pulse 110/min, and blood pressure 130/70 mm Hg. She is at the 5^th percentile for height. Physical examination reveals a webbed neck, cubitus valgus, and mild lymphedema of the upper extremities. Which of the following best describes the hormonal imbalances associated with this patient’s condition?

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A table shows hormone levels: Estradiol and Progesterone are down, while Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH) are up.

A table lists Estradiol, Follicle stimulating hormone (FSH), Luteinizing hormone (LH), and Progesterone. All values are labeled as "Unchanged."

A table shows hormone levels. Estradiol and Progesterone are up. Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH) are down.

A table lists hormones: Estradiol, Follicle stimulating hormone (FSH), Luteinizing hormone (LH), and Progesterone. Each hormone has a downward arrow indicating a decrease.

A table shows hormone levels. Estradiol is up, FSH is down, LH is down, and Progesterone is unchanged.