Disorders of sexual development and sex hormones Quiz: Ace Your Exams

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A 15-year-old boy presents to his family physician for a routine school physical. The patient appears anxious and uneasy during the encounter. During the physical exam, the patient confesses that he feels insecure about his body. During gym practice, the patient has noticed that his genitalia appears different from his peers. There is no history of a disorder of sexual development within the family. The patient’s height and weight are at the 56^th and 45^th percentile for his age, respectively. On physical examination, ambiguous genitalia are present with a bifid scrotum, undescended testicles and hypospadias. Laboratory testing reveals an increased testosterone to dihydrotestosterone ratio. Which of the following is likely true regarding this patient’s parents?

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Both parents are homozygous recessive.

The patient’s mother is homozygous dominant.

Both parents are heterozygous.

Neither parent possesses an allele for the disease.

The patient’s father is homozygous recessive.