Febrile neutropenia Quiz: Ace Your Exams

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A 77-year-old woman is admitted to the hospital for febrile neutropenia and started on cefepime. The patient is currently receiving chemotherapy for colon cancer. Initial workup including urinalysis, chest radiograph, and nasal viral swab did not reveal a source of infection. On day two of hospitalization, the patient's blood culture from the chest wall port demonstrates growth of Staphylococcus aureus with sensitivities pending, and results from the other blood culture are pending. On rounds, the patient reports persistent chills throughout the night. Temperature is 38.2 °C (100.8 °F), pulse is 96/min, respiratory rate is 16/min, blood pressure is 130/60 mmHg, and oxygen saturation is 98% on room air. On physical examination, there is no erythema or purulence at the right chest wall port. Which of the following is the best next step in management?  

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