Gastric cancer Quiz: Ace Your Exams

Get ready to dominate your medical and nursing exams by using our dynamic quizzes to elevate your knowledge and increase your confidence. Whether you're gearing up for the USMLE®, COMLEX®, or your next in-class assessment, Osmosis quizzes tackle key topics in pathology, diagnostics, and treatment approaches. By honing in on clinical readiness and decision-making, we make sure the knowledge you gain empowers you both in the classroom and in real-world practice. Jump in and supercharge your exam prep!

Learning videos

Flashcards

Expert reviewed

Spaced Repetition

Mobile app

Custom Quizzes

1 of 4

A 44-year-old woman comes to the primary care physician with a several month history of worsening epigastric pain, weight loss, and early satiety. The patient reports she has lost 11.3 kg (25-lbs) in the last 3 months. Physical examination shows a thin, middle-aged female with hyperpigmented, velvety axillary skin folds and tenderness to palpation in the epigastrium. A secretin stimulation test results in a < 200 ng/L increase in serum gastrin. An upper endoscopy with biopsy is performed, demonstrating the following histologic image. Which of the following is the underlying genetic mutation causing this disease process?

A close-up, high-magnification view of stained tissue showing various cells, some with prominent nuclei and others appearing as faint, irregular shapes.

A close-up, high-magnification view of stained tissue showing various cells, some with prominent nuclei and others appearing as faint, irregular shapes.

Reproduced from: wikipedia

Elimination tool

Choose an option:

Autosomal dominant inheritance of a mutation LKB1

Autosomal dominant mutation of APC tumor suppressor gene on chromosome 5q

Autosomal dominant inheritance of a mutation in MEN1

Loss of cell adhesion protein E-cadherin

Increased activation of transforming growth factor-alpha (TGFa)