Gastroesophageal reflux disease (GERD) Quiz: Ace Your Exams
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A 46-year-old man presents to the primary care physician with a 6 month history of worsening retrosternal burning pain and coughing after eating. The patient reports he has had similar symptoms over the past 10 years but states they have never been this severe. The patient has smoked 1 pack of cigarettes daily for 30 years. The patient's family history is significant for esophageal adenocarcinoma in his older brother. An esophagogastroduodenoscopy is performed, and an image of the gastroesophageal junction is shown below:

Reproduced from: Wikipedia
A biopsy of this lesion is most likely to demonstrate which of the following pathological changes?

Reproduced from: Wikipedia
A biopsy of this lesion is most likely to demonstrate which of the following pathological changes?
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