Gestational trophoblastic disease (GTD) and neoplasia (GTN) Quiz: Ace Your Exams
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A 40-year-old woman, gravida 1 para 1, presents to the emergency department for evaluation of abnormal vaginal bleeding, pelvic pain, and severe nausea and vomiting. The patient has a history of irregular menstrual cycles, and the first day of her most recent menstrual period was 10 weeks ago. She began bleeding five days ago and thought it was her regular period. The nausea and vomiting have been worsening over the past week, and today the pelvic pain increased, and she began passing grape-like clusters of tissue. Temperature is 36.9°C (98.4°F), pulse is 96/min, respirations are 14/min, and blood pressure is 136/90 mmHg. On exam, the uterus is enlarged, and bilateral adnexal masses are palpated. Quantitative human chorionic gonadotropin (hCG) is 250,000 IU/mL. Pelvic ultrasound shows an intrauterine mass with diffuse anechoic spaces, and no gestational sac. Large multilocular adnexal cysts are noted bilaterally. Which of the following would be the most likely finding on cytogenetic analysis of an intrauterine specimen?
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