Glucose-6-phosphate dehydrogenase (G6PD) deficiency Quiz: Ace Your Exams
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A 70-year-old man comes to the emergency department due to a syncopal episode that he experienced while playing with his grandchildren. He reports new exercise intolerance over the past few months, noting that he now cannot reach the mailbox without experiencing chest pain and shortness of breath. He also notes that his urine appears darker than normal. His past medical history is significant for hypertension and gastroesophageal reflux disease. He denies alcohol or tobacco use. His temperature is 37°C (98.6°F), pulse is 88/min, respirations are 22/min, and blood pressure is 138/82 mmHg. The patient appears pale. A systolic ejection murmur over the 2nd right intercostal space with radiation to the carotids is heard on auscultation. Laboratory tests are obtained and results are shown below.
Which of the following are most likely seen on this patient’s peripheral blood smear?
| Laboratory value | Result |
| Hematologic | |
| Hemoglobin | 9.2 g/dL |
| Mean corpuscular volume (MCV) | 88 fL |
| Platelet count | 280,000/mm3 |
| Reticulocyte count | 4.2% |
| Blood, plasma, serum | |
| Lactate dehydrogenase (LDH) | 1380 U/L |
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