Hypothyroidism Quiz: Ace Your Exams

Get ready to dominate your medical and nursing exams by using our dynamic quizzes to elevate your knowledge and increase your confidence. Whether you're gearing up for the USMLE®, COMLEX®, or your next in-class assessment, Osmosis quizzes tackle key topics in pathology, diagnostics, and treatment approaches. By honing in on clinical readiness and decision-making, we make sure the knowledge you gain empowers you both in the classroom and in real-world practice. Jump in and supercharge your exam prep!

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A 48-year-old woman comes to the physician complaining of an enlarging painless neck mass. She first noticed the mass 3 weeks ago and reports that it has gotten progressively larger over time. The patient has also gained 10-lb in the last 6 weeks, and frequently has to wear a sweater when taking a walk in the park, even on hot days. She has not experienced any night sweats or fevers. Temperature is 37.0°C (98.6°F), pulse is 52/min, blood pressure is 124/88 mm Hg, and BMI is 27 kg/m2. Palpation of the neck reveals a fixed, hard, painless goiter. There is delayed tendon reflex relaxation in the lower extremities. A biopsy of the mass is performed, which shows compression of follicles by extensive dense fibrous tissue. Laboratory studies are done and show the following:  
 
 Laboratory value  Result 
 ESR  6 mm/h 
 TSH  7.1 μU/mL 
 Anti-thyroid peroxidase   Negative 
 Anti-thyroglobulin antibody  Negative  
 
If left untreated, which of the following is likely to be seen in this patient?

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