Immune thrombocytopenia Quiz: Ace Your Exams
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A 30-year-old woman, gravida 1 para 1, at 14 weeks gestation, comes to the clinic for evaluation of easy bruising and a rash on her legs. She has been taking naproxen daily for the past two weeks for nonspecific back pain. Past medical history is unremarkable. Vitals are within normal limits. Physical examination shows petechiae on the lower extremities bilaterally and multiple small ecchymoses on the extremities. Abdominopelvic examination shows a gravid uterus 4 cm below the umbilicus. The remainder of the examination is unremarkable. Initial laboratory evaluation is shown below. The peripheral smear shows normal red blood cells without platelet clumping. Which of the following is the most likely cause of thrombocytopenia in this patient?
| Laboratory test | Result |
| Hemoglobin | 12.2 g/dL |
| Leukocyte count | 4900/μL |
| Platelet count | 45,000/μL |
| Creatinine | 0.7 mg/dL |
| Prothrombin time (PT) | 12 s |
| Activated partial thromboplastin time (aPTT) | 22 s |
| International normalized ratio (INR) | 1.1 |
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