Immunodeficiencies Quiz: Ace Your Exams

Get ready to dominate your medical and nursing exams by using our dynamic quizzes to elevate your knowledge and increase your confidence. Whether you're gearing up for the USMLE®, COMLEX®, or your next in-class assessment, Osmosis quizzes tackle key topics in pathology, diagnostics, and treatment approaches. By honing in on clinical readiness and decision-making, we make sure the knowledge you gain empowers you both in the classroom and in real-world practice. Jump in and supercharge your exam prep!

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An 18-month-old boy is brought to the emergency department for evaluation of shortness of breath and cough. Past medical history includes two episodes of pneumonia, oral thrush, chronic diarrhea and recurrent otitis media. His vaccinations are not up to date due to frequent illnesses. Family history is non-contributory. The patient is at the 2nd percentile for height and weight. Temperature is 38.7 C (101.7 F), pulse is 151/min, respirations are 36/min and blood pressure is 70/40 mmHg. Physical examination demonstrates white patches in the oral cavity and diffuse rales of the lungs bilaterally. Laboratory results are demonstrated below.

 
 Complete blood count 
 Leukocyte count  8,100 /mm3 
 Platelet count  300,000/mm3 
 Lymphocytes  5% 
 CD 19+  low 
 CD 3+  absent 
 Immunoglobulins 
 IgG  220mg/dL 
 IgA  40 mg/dL 
 IgM  15 mg/dL 

Chest X-ray demonstrates bilateral diffuse interstitial infiltrates. Which of the following is the most likely diagnosis?

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