Intrinsic hemolytic normocytic anemia Quiz: Ace Your Exams

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A 16-year-old African American boy presents to the emergency department with sudden onset of weakness, shortness of breath, and fatigue. The patient denies chest pain, and his mother explains that the patient has had symptoms of “the common cold” for the past few days. Family history includes sickle cell disease. Temperature is 37°C (98.9°F), pulse is 91/min, respirations are 19/min, and blood pressure is 126/76 mmHg. Physical examination reveals scleral icterus and pallor. Cardiopulmonary examination is within normal limits, and abdominal examination does not reveal hepatosplenomegaly. Chest x-ray is within normal limits. Laboratory tests are obtained, and the results are shown below.


Which of the following is the most likely diagnosis?

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