Jaundice Quiz: Ace Your Exams
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A 57-year-old man comes to his primary care physician for evaluation of abdominal pain and fatigue. His symptoms began 4 months ago and have progressively worsened. In addition, he reports a 5 kg (11 lb) unintentional weight loss since symptom onset. The patient often wakes up at night drenched in sweat. Past medical history is notable for peripheral vascular disease and alcohol use disorder. The patient has a 40-pack-year smoking history. Physical examination shows jaundice and scleral icterus. Abdominal pain is most prominent in the epigastric region. Laboratory testing reveals the following findings:
*Normal range: 12-70 U/L
Which of the following additional findings will be most likely present on this patient’s physical examination?
| Laboratory value | Result |
| Total bilirubin | 5.2 mg/dL |
| Conjugated bilirubin | 4.6 mg/dL |
| Alkaline phosphatase | 96 U/L |
| Aspartate transaminase | 110 U/L |
| Alanine transaminase | 112 U/L |
| Lipase* | 95 U/L |
Which of the following additional findings will be most likely present on this patient’s physical examination?
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