Leukemias Quiz: Ace Your Exams

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 40-year-old woman is brought to the emergency department because of recurrent epistaxis and ongoing gingival bleeding. She has no history of trauma. Past medical history is noncontributory. Family history is significant for hemophilia A in her brother. Temperature is 37.0°C (98.6°F), pulse is 125/min, respirations are 20/min, and blood pressure is 105/75 mmHg. Physical examination shows mucosal pallor and petechiae on the lower extremities. There is ongoing oozing of blood from the gingiva. Laboratory studies are shown:  
 
 Laboratory value  Result 
 Complete blood count 
 Hemoglobin   8.6 g/dL 
 Platelets   60,000/mm3 
 Leukocytes   3,500/mm3 
 Coagulation profile 
 Prothrombin time (PT)  25 sec 
 Activated partial thromboplastin time (aPTT)  50 sec 
 Bleeding time (BT)   11 minutes 
 Plasma fibrinogen  150 mg/dL   (N = 200-400 mg/dL) 
 D-dimer   1200 ng/dL   (N = <500 ng/mL) 

After stabilization and appropriate workup, bone marrow biopsy is performed and is shown below:


Retrieved from: Wikimedia Commons  

Chromosomal analysis of the abnormal cells will most likely show which of the following abnormalities?   

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Choose an option: