Lung cancer and mesothelioma Quiz: Ace Your Exams

Get ready to dominate your medical and nursing exams by using our dynamic quizzes to elevate your knowledge and increase your confidence. Whether you're gearing up for the USMLE®, COMLEX®, or your next in-class assessment, Osmosis quizzes tackle key topics in pathology, diagnostics, and treatment approaches. By honing in on clinical readiness and decision-making, we make sure the knowledge you gain empowers you both in the classroom and in real-world practice. Jump in and supercharge your exam prep!

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A 60-year-old man comes to the office because of a 6-month history of cough, dyspnea, and weakness. He describes difficulty getting up from a seated position and often needs assistance when rising from the couch. The weakness is worse when he wakes up and improves after he finishes his morning exercise and walks around. Medical history is significant for appendectomy 10 years ago and smoking 1.5 packs per day for 35 years. Physical examination reveals decreased tendon reflexes in the upper and lower extremities. An x-ray of the chest shows flattening of the diaphragm and elongation of the mediastinum, as well as a 2-cm nodule near the hilum. Biopsy of the nodule is most likely to yield which of the following histological findings?

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Small dark cells, and positive staining for synaptophysin

Undifferentiated pleomorphic giant cells

Columnar cells containing mucus, and positive staining for mucin

Epithelioid macrophages and multinucleated giant cells, surrounded by a concentric rim of CD4+ lymphocytes

Thin cells, keratinized complexes and intercellular bridges