Myasthenia gravis Quiz: Ace Your Exams
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A 37-year-old woman presents to the ophthalmologist for evaluation of double vision. She complains of intermittent horizontal diplopia over the past two weeks that worsens as the day progresses, especially with looking up. In the evenings, her eyelids become droopy despite not feeling tired. She has no significant past medical history and takes no medication. She has astigmatism but does not require prescription lenses. Temperature is 37.0°C (98.6°F), pulse is 68/min, respirations are 12/min, blood pressure is 120/80 mmHg, and oxygen saturation is 97 on room air. On exam, there is bilateral ptosis that worsens with sustained upward gaze. Improvement of ptosis is seen after the application of ice packs over the eyes for two minutes. Bilateral limb strength, deep tendon reflexes, and sensory exam are normal. Laboratory testing for disease-specific antibodies is negative. Which of the following is the most appropriate diagnostic study to obtain now?
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