Plasma cell disorders Quiz: Ace Your Exams
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A 61 year-old man presents to his outpatient provider’s office for a health maintenance visit. Apart from mild lower back and right knee pain that worsens with movement and improves with ibuprofen, the patient reports feeling well. Past medical history is notable for hypertension. His body-mass index (BMI) is 31 kg/m2. Physical exam reveals limited range of motion and crepitus in the right knee. There is no tenderness to palpation along the patient’s spine. Laboratory testing results are as follows:
Plasma protein electrophoresis reveals an elevated monoclonal immunoglobulin count. In addition to informing the patient of these findings, which of the following is the patient at risk of developing?
| Laboratory value | Result | Reference Range |
| Hemoglobin | 15.1 g/dL | 13.5-17.5 g/dL |
| Leukocyte count | 4800/mm3 | 4,500-11,000/mm3 |
| Creatinine | 0.9 mg/dL | 0.6-1.2 mg/dL |
| Calcium | 9.1 mg/dL | 8.4-10.2 mg/dL |
| Aspartate aminotransferase (AST) | 17 U/L | 8-40 U/L |
| Alanine aminotransferase (ALT) | 12 U/L | 8-40 U/L |
Plasma protein electrophoresis reveals an elevated monoclonal immunoglobulin count. In addition to informing the patient of these findings, which of the following is the patient at risk of developing?
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