Pulmonary transfusion reactions Quiz: Ace Your Exams

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A 58-year-old man is undergoing a red blood cell transfusion. Thirty minutes into the transfusion, he suddenly develops dyspnea, cough, and chest tightness. Past medical history is significant for hypertension and type 2 diabetes mellitus. Temperature is 38.7°C (101.7°F), heart rate is 110/min, respiratory rate is 28/min, blood pressure is 90/50 mmHg, and oxygen saturation is 88% on room air. On physical examination, he appears anxious and tachypneic. There is no rash or urticaria. Auscultation of the lungs reveals bilateral rales without wheezing. There is no lower extremity edema. Which of the following is the best next step in management?  

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