Rheumatoid arthritis Quiz: Ace Your Exams
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A 48-year-old woman presents to the office for evaluation of bilateral hand pain and morning stiffness for 6 months. The stiffness lasts for 60 minutes each morning, making it challenging for her to button her shirt and get ready. It gradually improves throughout the morning and is not as noticeable throughout the rest of the day. She also has fatigue which started 5 months ago, but she does not have fever, chills, weight loss, rashes, or hair loss. She has no significant past medical history. Temperature is 37.1°C (98.7°F), pulse is 82/minute, respiratory rate is 18/minute, and blood pressure is 126/74 mmHg. Physical examination of the hands shows tenderness and swelling with a “boggy” feel on palpation of the bilateral proximal interphalangeal (PIP) and metacarpophalangeal (MCP) joints of the hands. There is no warmth on palpation of the joints. Laboratory results are shown below. Which of the following tests should be ordered next to help make the diagnosis?
| Laboratory value | Result | Reference range |
| Leukocyte count | 9,000/mm3 | 4,500-11,000/mm3 |
| Erythrocyte sedimentation rate | 35 mm/hr | 0-20 mm/hr |
| Rheumatoid factor | 1:40 | <1:80 |
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