Sepsis (pediatrics) Quiz: Ace Your Exams

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4-year-old boy presents to the emergency department with his parents for evaluation of a fever. Parents state the patient suffers from recurrent urinary tract infections (UTI) due to duplication of the collecting system and are concerned that he may have another UTI. The patient does not have a cough, congestion, or increased work of breathing. The patient has no other significant medical history. There are no known sick contacts. Patient is 38th percentile for weight and 52nd percentile for height. Temperature is 38.8°C (101.8°F), blood pressure is 75/32 mmHg, pulse is 140/min, respiratory rate is 20/min, and oxygen saturation is 99% on room air. The patient is sitting in his parent’s lap in no acute distress. Mucous membranes are dry. Cardiopulmonary examination reveals tachycardiadelayed capillary refill, and lungs are clear to auscultation bilaterally. Abdominal examination reveals suprapubic tenderness and left costovertebral angle tenderness. The results of initial laboratory studies are shown belowThe patient is provided with intravenous fluids with improvement in blood pressure and capillary refill and empiric antibiotics are started based on the most likely diagnosis. Which of the following best describes this patientdisease process? 

 Laboratory value     Result   
 Serum chemistry    
 Sodium      131 mEq/L    
 Potassium      3.9 mEq/L    
 Chloride      97 mEq/L    
 Creatinine      2.6 mg/dL    
 Albumin      3.2 g/dL    
 Urine    
 Erythrocytes     0/hpf    
 Leukocytes     100-150/hpf    
 WBC Esterase      Large        
 Nitrite     Positive    
 Bacteria      Large    
 Complete blood count         
 Hemoglobin     12.5  g/dL    
 Hematocrit     36.8%    
 Leukocyte count     19,100/mm3    
 Platelet count     400,000/mm3    

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