Sickle cell disease Quiz: Ace Your Exams
Get ready to dominate your medical and nursing exams by using our dynamic quizzes to elevate your knowledge and increase your confidence. Whether you're gearing up for the USMLE®, COMLEX®, or your next in-class assessment, Osmosis quizzes tackle key topics in pathology, diagnostics, and treatment approaches. By honing in on clinical readiness and decision-making, we make sure the knowledge you gain empowers you both in the classroom and in real-world practice. Jump in and supercharge your exam prep!
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A 25-year-old man presents to the clinic for follow-up after being discharged from the hospital for acute chest syndrome. He was diagnosed with sickle cell disease (SCD) in childhood. Additional past medical history includes frequent hospitalizations for painful episodes and a cholecystectomy at age 21 due to chronic cholelithiasis. He takes folic acid daily. His temperature is 37.1°C (98.8°F), blood pressure is 125/80 mm Hg, pulse is 78/min, respiratory rate is 15/min, and oxygen saturation is 96% on room air. Physical examination shows pallor, scleral icterus, and the absence of a palpable spleen on abdominal examination. Laboratory results are shown below. Hemoglobin electrophoresis reveals 85% hemoglobin S and 15% hemoglobin F. Which of the following is the next best step in management?
| Laboratory test | Results |
| Hemoglobin | 8.8 g/dL |
| WBC | 12,000/mm2 |
| Platelets | 370,000/mm2 |
| Sodium | 138 mEq/L |
| Potassium | 4.1 mEq/L |
| Chloride | 102 mEq/L |
| Bicarbonate | 24 mEq/L |
| Total Bilirubin | 3.5 mg/dL |
| Direct Bilirubin | 0.8 mg/dL |
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