Skin cancer Quiz: Ace Your Exams
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A 55-year-old healthy man comes to the office because of an evolving nevus. He states it has been present on the dorsum of his right hand for “quite a while,” but it started growing in size and changing color recently. He has been a gardener for the past 20 years and spends much of his time working outdoors. Physical examination shows a hyperpigmented lesion on the dorsum of the right hand with irregular borders, measuring 8-mm in diameter. Excisional biopsy of the lesion reveals the following findings on histopathology.

Which of the following is associated with the highest risk of metastasis for this patient’s lesion?

Which of the following is associated with the highest risk of metastasis for this patient’s lesion?
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