Skin cancer Quiz: Ace Your Exams

Get ready to dominate your medical and nursing exams by using our dynamic quizzes to elevate your knowledge and increase your confidence. Whether you're gearing up for the USMLE®, COMLEX®, or your next in-class assessment, Osmosis quizzes tackle key topics in pathology, diagnostics, and treatment approaches. By honing in on clinical readiness and decision-making, we make sure the knowledge you gain empowers you both in the classroom and in real-world practice. Jump in and supercharge your exam prep!

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A 75-year-old man presents to the office for the evaluation of a lesion on his right forearm. He first noticed the lesion 9 months ago, and it has gradually increased in size since then. He has worked on various construction sites for the past 45 years. Past medical history is noncontributory. Family history is significant for skin cancer in his father. Physical examination shows a 1.5 cm nodule with a thick and rough surface on his right forearm. Biopsy of the lesion reveals atypical keratinocytes with keratin pearls and deep dermal invasion, as shown below:  

A high-magnification histopathology slide shows numerous keratin pearls, invasive islands, and nests of atypical squamous cells within a dense stroma.
Retrieved fromWikimedia Commons  

Which of the following additional features is most likely to be present in this patient?  

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