Suicide Quiz: Ace Your Exams
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A 28-year-old man presents to his primary care physician's clinic for evaluation of low energy and fatigue. He states he has been more stressed since being laid off from work six months ago. He used to work as an investment banker, and he has not had the motivation to look for a new job. He used to play the piano in his spare time, but he states he no longer enjoys it due to his inability to concentrate. His appetite has increased and he has gained 4.1-kg (9-lb) over this time. He awakens early in the morning and has difficulty going back to sleep. Vitals are within normal limits. Physical examination reveals a young, disheveled man who makes poor eye contact and speaks slowly. The remainder of the examination is noncontributory. The physician discusses several treatment options, and together they agree on combination treatment with cognitive behavioral therapy and sertraline. Which of the following best explains the mechanism of action of this medication?
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