Ulcerative colitis Quiz: Ace Your Exams
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A 52-year-old man comes to the office with complaints of intermittent abdominal cramps and diarrhea for the past 2 months. He has had 4-5 bowel movements per day containing small-volume stools that are mixed with blood and mucus. Review of systems reveals a 5.9-kg (13-lbs) weight loss, fatigue, and loss of appetite. He also experiences pain and tenderness in the right knee that responds to indomethacin. The remainder of the history is unremarkable. Vitals are within normal limits. Physical examination shows tenderness in the left lower quadrant without rebound or guarding. Laboratory results are as follows:
Colonoscopy shows erythematous and edematous bowel wall mucosa extending from the rectum to the sigmoid colon with small shallow ulcers throughout the involved region. Biopsy of the involved tissue sample will most likely show which of the following findings?
| Laboratory value | Result |
| Complete blood count | |
| Hemoglobin | 9.7 mg/dL |
| Platelets | 290,000/mm3 |
| Leukocytes | 13,200/mm3 |
| Erythrocyte sedimentation rate | 120 mm/hr |
Colonoscopy shows erythematous and edematous bowel wall mucosa extending from the rectum to the sigmoid colon with small shallow ulcers throughout the involved region. Biopsy of the involved tissue sample will most likely show which of the following findings?
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