Vaginal and vulvar disorders Quiz: Ace Your Exams
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A 62-year-old woman came to the clinic due to vaginal pruritus and eczema over the past month. She has tried multiple creams, including corticosteroids, with no relief. She is generally healthy and does not smoke or use alcohol. There is no history of sexually transmitted diseases or abnormal Pap smears. The patient has had 3-lifetime sexual partners and is currently in a monogamous relationship with her partner of 35 years. The patient’s temperature is 37.0°C (98.6°F), pulse is 76/min, and blood pressure is 142/86 mmHg. Physical examination reveals a well-demarcated, eczematous lesion with raised edges that covers most of the left labia majora. A biopsy is obtained and reveals tumor cells with clear cytoplasm (clear halo) infiltrating the epidermis, as shown below:

Which of the following is the most likely underlying cause of this patient’s condition?

Retrieved from: Wikimedia Commons
Which of the following is the most likely underlying cause of this patient’s condition?
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