Water-soluble vitamin deficiency and toxicity Quiz: Ace Your Exams
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A 42-year-old woman comes to the clinic with generalized fatigue and a sore throat for the past week. She has a 15-year history of celiac disease that is poorly controlled with diet, and she frequently has large, bulky stools multiple times per day. Past medical history also includes seborrheic dermatitis. Temperature is 37.0°C (98.6°F), pulse is 96/min, respirations are 20/min, and blood pressure is 135/85 mmHg. BMI is 19 kg/m2. She is alert, cooperative, and oriented to time, place, and person. Oral examination reveals hyperemia of pharyngeal membranes, edema of mucous membranes, glossitis and stomatitis.
On cardiac auscultation, S1 and S2 are normal, and no murmurs or gallops are heard. Laboratory investigations are shown below:
An underlying water-soluble vitamin deficiency is suspected. Which of the following biochemical conversions are impaired, considering the most likely deficiency in this patient?
On cardiac auscultation, S1 and S2 are normal, and no murmurs or gallops are heard. Laboratory investigations are shown below:
| Laboratory value | Result |
| Complete blood count | |
| Hemoglobin | 9 g/dL |
| Leukocyte count | 5,000 /mm3 |
| Platelet count | 150,000/mm3 |
| MCV | 88 fL |
An underlying water-soluble vitamin deficiency is suspected. Which of the following biochemical conversions are impaired, considering the most likely deficiency in this patient?
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