Assessment of Diamond-Blackfan anemia: Video, Causes, Symptoms | Osmosis

Question

A 25-year-old woman presents to her outpatient provider for symptoms of fatigue and reduced exercise tolerance that started 2 weeks ago. Past medical history is notable for seizure disorder that is currently managed with phenytoin. In addition, the patient had an episode of pyelonephritis several weeks ago that was successfully treated with trimethoprim-sulfamethoxazole. The patient has menstrual periods every 28 days, and denies dysmenorrhea and menorrhagia. Physical examination is notable for conjunctival pallor. Laboratory testing reveals a hemoglobin on 9.3 g/dL (reference range: 12-16 g/dL). A peripheral blood smear reveals hypersegmented neutrophils, as demonstrated by the following:

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Which of the following sets of red blood cell characteristics is most likely to be seen in this patient?

Accepted Answer

Impaired Process	Red Blood Cell Maturity	Mean Corpuscular Volume
DNA Synthesis	Immature	105 mm³

Answer

Impaired Process	Red Blood Cell Maturity	Mean Corpuscular Volume
DNA Synthesis	Immature	105 mm³

Answer

Impaired Process	Red Blood Cell Maturity	Mean Corpuscular Volume
DNA Synthesis	Immature	105 mm³

Answer

Impaired Process	Red Blood Cell Maturity	Mean Corpuscular Volume
DNA Synthesis	Immature	105 mm³

Answer

Impaired Process	Red Blood Cell Maturity	Mean Corpuscular Volume
DNA Synthesis	Immature	105 mm³

Diamond-Blackfan anemia

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