ECG basics

Last updated: June 19, 2025

ECG basics

FINAL

FINAL

ACE inhibitors, ARBs and direct renin inhibitors
Thiazide and thiazide-like diuretics
Calcium channel blockers
Adrenergic antagonists: Beta blockers
Acyanotic congenital heart defects: Pathology review
Atherosclerosis and arteriosclerosis: Pathology review
Coronary artery disease: Pathology review
Peripheral artery disease: Pathology review
Valvular heart disease: Pathology review
Cardiomyopathies: Pathology review
Heart failure: Pathology review
Supraventricular arrhythmias: Pathology review
Ventricular arrhythmias: Pathology review
Heart blocks: Pathology review
Aortic dissections and aneurysms: Pathology review
Pericardial disease: Pathology review
Endocarditis: Pathology review
Hypertension: Pathology review
Shock: Pathology review
Vasculitis: Pathology review
Cardiac and vascular tumors: Pathology review
Dyslipidemias: Pathology review
Cardiac tamponade
Endocarditis
Myocarditis
Rheumatic heart disease
Heart failure
Cor pulmonale
Long QT syndrome and Torsade de pointes
Ventricular tachycardia
Premature ventricular contraction
Ventricular fibrillation
Atrial flutter
Premature atrial contraction
Atrial fibrillation
Atrioventricular nodal reentrant tachycardia (AVNRT)
Deep vein thrombosis
Hypotension
Orthostatic hypotension
Polycystic kidney disease
Pheochromocytoma
Cushing syndrome
Renal artery stenosis
Hypertension
Aneurysms
Aortic dissection
Peripheral artery disease
Angina pectoris
Unstable angina
Prinzmetal angina
Myocardial infarction
Stable angina
Arterial disease
ECG normal sinus rhythm
ECG cardiac hypertrophy and enlargement
ECG cardiac infarction and ischemia
ECG basics
ECG intervals
ECG axis
ECG QRS transition
ECG rate and rhythm
Cardiac conduction system
Cardiac conduction velocity
Normal heart sounds
Abnormal heart sounds
Cardiovascular changes during postural change
Cardiovascular changes during hemorrhage
Cardiac preload
Cardiac contractility
Cardiac afterload
Measuring cardiac output (Fick principle)
Thrombocytopenia: Clinical
Heparin-induced thrombocytopenia
Immune thrombocytopenia
Gout
Chronic kidney disease: Clinical
Traumatic brain injury: Pathology review
Traumatic brain injury: Clinical
Concussion and traumatic brain injury
Blood groups and transfusions
Blood products and transfusion: Clinical
HIV (AIDS)
Hodgkin lymphoma
Acromegaly
Musculoskeletal injuries: Nursing process (ADPIE)
Hemophilia: Nursing process (ADPIE)
Diabetes insipidus
Diabetes mellitus
Diabetes mellitus: Clinical
Diabetes mellitus: Pathology review
Diabetes mellitus (DM): Nursing process (ADPIE)
Diabetes insipidus: Nursing process (ADPIE)
Managing diabetes during the holidays: Information for patients and families
Hypoglycemics: Insulin secretagogues
Insulins
Epistaxis: Nursing process (ADPIE)
Appendicitis
Appendicitis: Clinical
Appendicitis: Pathology review
Appendicitis: Nursing process (ADPIE)
Hypothyroidism medications
Hyperosmolar hyperglycemic state (HHS): Nursing process (ADPIE)
Sympathomimetics: Direct agonists
Cushing syndrome and Cushing disease: Pathology review
Cushing syndrome: Clinical
Metabolic and respiratory alkalosis: Clinical
Metabolic and respiratory acidosis: Clinical
Conjunctivitis: Nursing process (ADPIE)
Stroke: Clinical
Stroke: Nursing process (ADPIE)
Peptic ulcer
Peptic ulcer disease (PUD): Nursing process (ADPIE)
Peptic ulcers and stomach cancer: Clinical
Gallbladder histology
Gallbladder disorders: Clinical
Acute cholecystitis
Oral cancer
Hepatitis A and Hepatitis E virus
Viral hepatitis: Clinical
Hepatitis medications
Seizures: Pathology review
Seizures: Clinical
Seizures and epilepsy
Febrile seizure
Seizure disorder: Nursing process (ADPIE)
Non-urothelial bladder cancers
Inflammatory bowel disease: Clinical
Inflammatory bowel disease: Pathology review
Anticoagulants: Heparin
Postoperative evaluation: Clinical
Trigeminal neuralgia
Trigeminal neuralgia: Nursing process (ADPIE)
Hypoparathyroidism
Pancreatitis: Pathology review
Pancreatitis: Clinical
Acute pancreatitis
Pancreatitis: Nursing process (ADPIE)
Chronic pancreatitis
Sickle cell disease (NORD)
Sickle cell disease: Clinical
Sickle cell disease: Nursing process (ADPIE)
Class IV antiarrhythmics: Calcium channel blockers and others
Hypertension: Clinical
Pulmonary hypertension
Hypertension: Nursing process (ADPIE)
Osteoarthritis
Joint pain: Clinical
Hyperthyroidism: Pathology review
Hyperthyroidism: Clinical
Deep vein thrombosis and pulmonary embolism: Pathology review
Hyperthyroidism
Hyperthyroidism medications
Hyperthyroidism: Nursing process (ADPIE)

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An electrocardiogram is also known as an ECG; the Dutch and German version of the word, elektrokardiogram, is shortened to EKG. It is a tool used to visualize, or “gram,” the electricity, or “electro,” that flows through the heart, or “cardio.” Specifically, a 12-lead ECG tracing shows how the depolarization wave, which is a wave of positive charge, moves during each heartbeat, by providing the perspectives of different sets of electrodes. This particular set of electrodes is called lead II; one electrode is placed on the right arm and the other on the left leg. Essentially, when the wave’s moving toward the left leg electrode, you get a positive deflection. This big, positive deflection corresponds to the wave moving down the septum.

To understand the basics, let’s start with an example of how we can look at the heart with only one pair of electrodes: a positive and a negative one. These electrodes detect the charge on the outside of the cell. Remember, at rest, cells are negatively charged relative to the slightly positive outside environment; let’s make these cells red. When they depolarize, the cells become positively charged, and leave a slightly negative charge in the outside environment; let’s make these cells green. Now, if we freeze this “wave of depolarization” as it’s moving through the cells, half of the cells are negative, or depolarized, and half are positive and resting; therefore, there’s a difference of charge across this set of cells. You can think of the charge difference as being a dipole, because there are two electrical poles. We can draw this dipole out as an arrow, or vector, pointing towards the positive charge. Remember, the electrodes detect charge on the outside of the cell, so this points toward where the positive charge is, outside.

Now, if there’s a dipole vector pointing toward the positive electrode, then the ECG tracing shows it as a positive deflection; the bigger the dipole is, the bigger the deflection is. If we unpause this, then everything becomes depolarized. Since there’s no difference in charge, there’s no dipole, and thus no deflection. Moments later, a wave of repolarization goes through, and the cells become negative once again. Pausing halfway through again, now the vector dipole goes in the opposite direction, and faces the negative electrode; this means that there will be a negative ECG tracing. Again, the bigger the dipole is, the bigger the negative deflection is. Even though it’d be nice if the depolarization wave lined up perfectly with the electrodes, usually that’s not the case. So, we simply look at the vector component that is parallel to that electrode. For example, let’s say that the depolarization happened this way, at an angle; then, we’d simply break the vector into two parts. The one we care about is the one that’s going towards the positive electrode, which causes a deflection, even though it’s a slightly smaller deflection than previously. In other words, the size of the deflection on the ECG tracing always corresponds to the magnitude, or size, of the dipole in the direction of the electrode. The perpendicular component isn’t pointing at the electrodes, so it doesn’t cause any deflection. In fact, if there’s a depolarization wave that goes straight up, perpendicular to the positive and negative electrodes, there would be no deflection!

In a standard ECG, there are 10 electrodes: four limb electrodes, with one each on the left arm, right arm, left leg, and right leg; and six precordial electrodes, V1 through V6, that wrap around the chest. The right leg electrode is usually used as a neutral lead. The heart is a three-dimensional organ, so V1 through V6 line up in the transverse, or horizontal, plane of the heart. Each electrode is set up to detect any wave of positive charge coming towards it. These are collectively called the chest leads.

Sources

  1. "Medical Physiology" Elsevier (2016)
  2. "Physiology" Elsevier (2017)
  3. "Human Anatomy & Physiology" Pearson (2017)
  4. "Principles of Anatomy and Physiology" Wiley (2014)
  5. "Screening for Cardiovascular Disease Risk With Electrocardiography" JAMA (2018)
  6. "Screening for Coronary Heart Disease With Electrocardiography: U.S. Preventive Services Task Force Recommendation Statement" Annals of Internal Medicine (2012)
  7. "Activation of the Interventricular Septum" Circulation Research (1955)