Quiz: Ace Your Exams
Get ready to dominate your medical and nursing exams by using our dynamic quizzes to elevate your knowledge and increase your confidence. Whether you're gearing up for the USMLE®, COMLEX®, or your next in-class assessment, Osmosis quizzes tackle key topics in pathology, diagnostics, and treatment approaches. By honing in on clinical readiness and decision-making, we make sure the knowledge you gain empowers you both in the classroom and in real-world practice. Jump in and supercharge your exam prep!
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A 65-year-old man comes to the office because of a positive fecal occult blood test during routine colorectal cancer screening. The patient has not experienced fatigue, changes in bowel habit, or recent weight loss. His medical and family history are noncontributory. His temperature is 36.2°C (97.1°F), pulse is 98/min, and blood pressure is 110/70 mm Hg. Physical examination shows no abnormalities. Complete blood count reveals a hemoglobin of 14 g/dL and mean corpuscular volume of 80 μm3. Colonoscopy demonstrates two polyps in the sigmoid colon, which are then biopsied. Histological images of the polyps are shown below: 
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Which of the following gene mutations is responsible for the conversion of normal colon to the lesion found in this patient?
Image reproduced from Wikimedia Commons
Which of the following gene mutations is responsible for the conversion of normal colon to the lesion found in this patient?
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