Osmosis video - Adrenal insufficiency: Clinical

Addison's disease, or adrenal insufficiency, is a rare disorder that occurs when the adrenal glands do not produce enough hormones. Adrenal insufficiency can be caused by several conditions, including autoimmune disease, infection, or failure of the adrenal glands.

Symptoms of adrenal insufficiency include fatigue, muscle weakness, weight loss, darkening of the skin (hyperpigmentation), and low blood pressure. Addison's disease is a serious condition that can be life-threatening if not treated properly.